The process of creating high-quality labeled data is crucial for training machine-learning models, but it can be a time-consuming and labor-intensive process.Moreover, manual annotation by human annotators can lead to varying degrees of competency, training, and experience, which can result in inconsistent labeling and arbitrary standards.To addres
Abstract Background Late-life depression (LLD) is a prevalent neuropsychiatric disorder in the older population.While LLD exhibits high mortality rates, depressive symptoms in older adults are often masked by physical health conditions.In younger adults, depression is associated with deficits in pupil light reflex and eye blink rate, suggesting the
Abstract Background Protein-DNA interaction governs a large number of cellular processes, and it can be altered by a small fraction of interface residues, i.e., the so-called hot spots, which account for most of the interface binding free energy.Accurate prediction of hot spots is critical to understand the principle of protein-DNA interactions.The
Abstract Background There is growing evidence of nervous system involvement and related complaints in children with coronavirus disease 2019 (COVID-19).However, it seems that attempts to track of the virus in the nervous system have so far been unsuccessful.Case presentation Here we describe two Throws pediatric cases of severe COVID-19 who had pos
Oculocutaneous albinism (OCA) is an inherited disorder affecting the visual system and skin pigmentation.Our aim was to evaluate genetic and clinical heterogeneity in a cohort of Slovenian paediatric patients with clinically suspected OCA using advanced molecular-genetics approach.In as much as 20 out of 25 patients, genetic variants explaining the